SUPPLEMENTS

Can Citicoline Really Improve Our Brain Function?

CHOLINE IS A CRITICAL NUTRIENT FOR BRAIN HEALTH BECAUSE OF

THE MANY METABOLIC PATHWAYS IT FEEDS INTO. WHAT HAS

SPARKED OUR INTEREST AT VYSANA IS THAT THERE IS A NUTRIENT

CALLED CITICOLINE, WHICH IS A NATURAL SOURCE OF CHOLINE.

Citicoline Is A Natural Source of Choline

Now you may already know that Choline is important for lipid (fatty acid), metabolism (breakdown) and liver health, but what has further intrigued us is how can we use a natural nutrient like Citicoline to improve our long-term brain health - is it all just a fad? Is it bio-hacking mumbo jumbo, or is there something beneficial in ensuring that we get enough of this important micronutrient in our diet? Brain health means different things to different people, but I'm sure you will agree that short-term memory, long-term memory, cognitive performance, and the ability to reduce the long-term risks of brain diseases like dementia and Alzheimer's are important to everyone. The question we have asked ourselves when researching the risks of cognitive decline, chronic cerebral disorders, and vascular cognitive impairment is? What can we do to minimise these risks?

HOW CITICOLINE WAS DISCOVERED

NOW THAT YOU ARE COMFORTABLE AND WE HAVE GOT YOUR COGNITIVE FUNCTIONING STEPPING UP A GEAR IN ANTICIPATION OF THE BENEFITS OF CITICOLINE, LET'S START FROM THE BEGINNING, AS ALL GOOD STORIES DO.

Can Citicoline Help With Cognitive Decline?

Citicoline is the name for a compound structurally identical to cytidine-diphosphocoline or CDP-choline. What we know is that it is naturally found in our bodies. It helps with the formation of cell membranes and plays a role in metabolism. It transmits messages throughout the brain, regulates chemical messengers called neurotransmitters (like dopamine), protects nerve cells from damage by blocking free radicals that cause oxidative stress, and helps synthesise higher-order thinking skills like attention span.

They found Citicoline Could Be Used To Increase Cognition in Stroke Patients:

In an earlier study at Johns Hopkins University, citicoline’s ability to provide neuroprotection for stroke patients indicated its potential as an aid in improving cognitive function. When they discovered that citicoline had this incredible mechanism of action, it prompted further research on how citicoline could be used to increase cognition, but also reduce cardiovascular risks associated with stroke.

So in the 1970’s citicoline was discovered by scientists from Johns Hopkins University, who were looking into citicoline's role in brain function and its potential as a therapy for neurodegenerative diseases like Parkinson's, Alzheimer's and ALS. In 1971, citicoline was approved as an orphan drug to treat vascular disorders, vascular cognitive impairment related to ageing, such as memory loss and dementia. Today, citicoline is one of the most important supplements on the market, because it provides many benefits, including increased cognition but also reducing cardiovascular risks associated with stroke.

Cognitive and Behavioural Disturbances and Chronic Cerebral Disorders... Citicoline also helps improve cardiovascular health

Nine facts about citicoline that support its use in helping with your cognitive health and potentially your overall health.

• Citicoline helps improve focus, so you can be more attentive and remember things better.
• Citocoline may help improve memory loss by using citicoline to increase acetylcholine production in the brain. Acetylcholine is one of the most important neurotransmitters for healthy cognition, so increasing its production should lead to improved cognitive function.....
• Citocoline may help reduce symptoms associated with menopause, such as mood swings, depression, and fatigue, that usually occur during this time of life.
• Citocoline helps improve your cardiovascular health because it prevents hypertension - which reduces risks related to a stroke or heart attack.
• Citicoline plays an essential role in fat metabolism and glucose regulation throughout the body, but also helps with weight management.
• Citocoline has shown improvement in brain disorders, such as patients with Alzheimer's disease, and has been effective in alleviating Parkinson's disease.

In older adults with cognitive impairment, supplementation with cognizin improved cognitive function, including short and long-term memory, attention, perceptual-motor capacity, and behavioural and emotional control.

A study by Eri Nakazaki concluded that “dietary supplementation of citicoline for 12-week improved memory performance, especially episodic memory, in healthy older males and females with AAMI”. The findings suggest that regular consumption of citicoline may be safe and potentially beneficial against memory loss due to ageing.

Cognizin ® is a branded form of Citicoline clinically studied to support mental energy, focus, and attention*. “The data from this analysis is encouraging that regular consumption of Cognizin ® citicoline may be safe and potentially beneficial against memory loss due to ageing"

SO IN CONCLUSION, LET'S LOOK AT: CITICOLINE, COGNIZIN,

MEMORY AND LONG TERM BRAIN HEALTH.

Citicoline is commonly found in brain health supplements alongside other nootropics like citiquinol, sulbutiamine and alpha-GPC. Citicoline has been shown to provide significant cognitive benefits that can enhance your mental acuity, memory recall skills, and mood under stress during all kinds of daily activities, such as business meetings or test taking at school. By maintaining higher levels of citicoline, you may reduce the risk of developing Alzheimer's Disease or dementia later in life, because it protects against free radical damage, which damages cells throughout your body, including neurons in the brain responsible for cognition. Citicoline is a safe, well-tolerated supplement with no known side effects when taken appropriately by healthy adults looking to boost their brain power naturally, without having to resort to potentially dangerous pharmaceuticals.

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